ERYTHROSINE

Overview

Chemical Names
DISODIUM 2',4',5',7'-TETRA-IODO-3',6'-DIOXIDOSPIRO-[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]- 3-ONE HYDRATE
Synonyms
C.I. FOOD RED 14; FD AND C RED No. 3
CAS number
16423-68-0
INS
127
Functional Class
Food Additives
COLOUR
INS matches
127

Evaluations

Evaluation year: 2018

ADI:
0-0.1 mg/kg bw

Comments:
The Committee concluded that the new data that have become available since the previous evaluation of erythrosine do not give reason to revise the ADI and confirmed the previous ADI of 0–0.1 mg/kg bw.
Meeting:
86
Specs Code:
R
Tox Monograph: 

Evaluation year: 1990

ADI:
0-0.1 mg/kg bw
Intake:
1999, TRS 896-JECFA 53/98,122; FAS 44-JECFA 53/499. The intake of erythrosine could exceed the ADI of 0-0.1 mg/kg bw if the maximum limits proposed in the draft General Standard for Food Additives being developed by the Codex Committee on Food Additives and Contaminants were widely adopted at the national level. Non-food sources of erythrosine, such as pharmaceutical products, should be included in intake assessments, as they may make a significant contribution to total intake if consumed over a long period. The Expert Committee concluded that long-term intake of erythrosine is unlikely to exceed the ADI, as erythrosine would be used in only a limited number of foods.
Meeting:
37
Specs Code:
R (1993)
Tox Monograph: 
Previous Years:
1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/51. R 1990, COMPENDIUM/569. R 1988, TRS 776-JECFA 33/18,FNP 38-JECFA 33/82, FAS 24-JECFA 33/39. 0-0.05 (TEMPORARY). TE. R 1986, TRS 751-JECFA 30/23, FNP 37-JECFA 30/45, FAS 21-JECFA 30/81. 0-0.6 (TEMPORARY). TE
1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/51. R 1990, COMPENDIUM/569. R 1988, TRS 776-JECFA 33/18,FNP 38-JECFA 33/82, FAS 24-JECFA 33/39. 0-0.05 (TEMPORARY). TE. R 1986, TRS 751-JECFA 30/23, FNP 37-JECFA 30/45, FAS 21-JECFA 30/81. 0-0.6 (TEMPORARY). TE