ROMPUM HYDROCHLORIDE

Overview

Chemical Names
2-(2,6-XYLIDINO)-5,6-DIHYDRO-4H-1,3-THIAZINE HYDROCHLORIDE; N-(2,6-DIMETHYLPHENYL)-5,6-DIHYDRO-4H-1,3-THIAZINE-2-AMINE HYDROCHLORIDE
Synonyms
BAY VA 1470; XYLAZINE HYDROCHLORIDE; ROMPUN HYDROCHLORIDE
Functional Class
Veterinary Drug
ADRENOCEPTOR_AGONIST

Evaluations

Evaluation year: 1998

ADI:
NO ADI ALLOCATED, genotoxic carcinogen

Comments:
The Committee was unable to establish an ADI for xylazine because it concluded that the 2,6-xylidine metabolite was genotoxic and carcinogenic.
MRL Comment:
No MRLs allocated as no ADI was established & residue data were insufficient.
MRL Code:
O
Meeting:
47
Report: 
TRS 876-JECFA 47/12
Tox Monograph: 
FAS 38-JECFA 47/45
Residues: 
FNP 41/9-JECFA 47/119