DDT

Overview

Chemical Names
1,1,1-TRICHLORO-2,2-bis(para-CHLOROPHENYL)ETHANE
CAS number
50-29-3
Functional Class
Food Contaminant
CONTAMINANT

Evaluations

Evaluation year: 1960

Comments:
In 2000 JMPR established a provisional tolerable daily intake (PTDI) of 0.01 mg/kg bw for DDT (FAO Plant Production and Protection Paper 163/ 59, Rome, 2001).
Intake:
Highest observed average intake: 0.68 mg/man/day
Tolerable Intake:
PTDI: 0.01 mg/kg bw/d
Meeting:
05

Toxicological study

Pivotal Study:
Hayes et al., 1956: 18-month clinical study (n=17/group), where volunteers ingested 0, 3.5, or 35 mg DDT/kg bw/d in capsules or milk emulsions. The last dose was approximately 0.5 mg/kg body-weight. No adverse effects were reported.
Animal Specie:
Human
Effect:
None reported
NOEL:
35 mg/kg bw/d
PTDI:
0-0.01 mg/kg bw
Point of departure:
0.5 mg kg bw/day