IPROPRAN
Overview
Chemical Names
2-ISOPROPYL-1-METHYL-5-NITROIMIDAZOLE; 1-METHYL-2-(1-METHYLETHYL)-5-NITRO-1H-
IMIDAZOLE
Synonyms
IPROPRAN
CAS number
14885-29-1
Functional Class
Veterinary Drug
ANTIPROTOZOAL_AGENT
ANTIPROTOZOAL_AGENT
Evaluations
Evaluation year: 1989
ADI:NO ADI ALLOCATED
ADI:
NO ADI ALLOCATED
Comments:
In a combined carcinogenicity and chronic toxicity study conducted with Sprague Dawley CFY rats, the Committee concluded that the results of this study indicated an effect of ipronidazole on mammary tumor formation in female rats in the high-dose group. However, the high incidence of tumors in the control animals, which is common in this rat strain, precluded the determination of a definite no-observed-effect level. As such, the Committee was not able to establish an ADI because the rat
carcinogenicity study was inadequate to determine a no-effect level for ipronidazole.
.
MRL Comment:
No MRLs allocated
MRL Code:
O
Meeting:
34
Report:
Tox Monograph:
Residues: