|Pivotal Study: ||Epidemiological study of prison inmates exposed to iodinated water (Thomas et al. (1978), Stockton & Thomas (1978), Thomas et al. (1969), and Freund et al. (1966)): 750 men and women that had ingested approximately one to two mg of iodine per day for various time periods. No adverse effects were reported except in four women who were hyperthyroid before entering became more symptomatic receiving the iodinated water supply, and that of 15 inmates tested, two had impaired organification of thyroidal iodine.