Monk Fruit Extract

Comments:

JECFA established a temporary ADI of 0–10 mg/kg bw per day, expressed as mogroside V, based on a NOAEL of 2144 mg/kg bw per day for mogroside V, the highest dose tested in a 52-week rat study and the application of a 200-fold uncertainty factor.

Intake:

JECFA considered that the conservative estimate of the highest dietary exposure to monk fruit extract (expressed as mogroside V) of 38 mg/kg bw per day for children was appropriate for the safety evaluation. However, it was noted that this estimate is based on proposed GSFA food categories and maximum levels. JECFA concluded that the current estimated dietary exposure to monk fruit extract (expressed as mogroside V) exceeds the temporary ADI by approximately four-fold, which would pose a potential safety concern under the proposed uses and proposed maximum levels.

Meeting:

102

Specs Code:

N, T