Teflubenzuron
Overview
Chemical Names
1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea
CAS number
83121-18-0
Functional Class
Veterinary Drug
INSECTICIDE
Veterinary Drug
INSECTICIDE
Veterinary Drug
Evaluations
Evaluation year: 2015
ADI:0–5 µg/kg bw
ADI:
0–5 µg/kg bw
Comments:
BMDL10 of 0.54 mg/kg bw per day for hepatocellular hypertrophy in male mice observed in the carcinogenicity study, with application of an uncertainty factor of 100.
No acute hazard.
MRL Comment:
The recommended MRL for teflubenzuron in salmon fillet (muscle plus skin in natural proportion) and in salmon muscle is 400 µg/kg.
Intake:
14 to 43% of the ADI for EDI and GECDE respectively.
Report:
Tox Monograph:
Residues:
Toxicological study
Pivotal Study:
Eighteen-month carcinogenicity study (diet) in mouse.