| SPA-20 | Hospital Universitario San Carlos | Madrid | SPAIN | EURO | WHO Collaborating Centre for Research & Training in Mental Health | SAXENA Shekhar | Active | Details |
| SPA-22 | Barcelona Public Health Agency | Barcelona | SPAIN | EURO | WHO Collaborating Centre for Occupational Health | PAUNOVIC Elizabet | Active | Details |
| SPA-27 | Instituto de Salud Carlos III | Madrid | SPAIN | EURO | WHO Collaborating Centre for Leishmaniasis | DAGNE Daniel Argaw | Active | Details |
| SPA-29 | European Institute of Health and Social Welfare | Madrid | SPAIN | EURO | WHO Collaborating Centre for Occupational Health | KORTUM Evelyn G. | Active | Details |
| SPA-30 | Instituto de Salud Carlos III | Majadahonda | SPAIN | EURO | WHO Collaborating Centre for Research, Reference and Training on Molecular Characterization of HIV | FRUTH Ulrich Josef | Active | Details |
| SPA-33 | Institut Catala D'oncologia, Departament De Salut | Barcelona | SPAIN | EURO | WHO Collaborating Centre for Public Health Palliative Care Programmes | TSOUROS Agis | Active | Details |
| SPA-34 | Organizacion Nacional de Trasplantes (ONT) | Madrid | SPAIN | EURO | WHO Collaborating Centre on Donation and Transplantation | NOEL Luc P.J. | Active | Details |
| SPA-37 | Universidad de Valencia | Valencia | SPAIN | EURO | WHO Collaborating Centre on Fascioliasis and Its Snail Vectors | ENGELS Dirk A. | Active | Details |
| SPA-38 | University of Navarra | Pamplona | SPAIN | EURO | WHO Collaborative Centre for Injury Prevention | SETHI Dinesh | Active | Details |
| SPA-42 | University of Alicante- Universidad de Alicante | Alicante | SPAIN | EURO | WHO Collaborating Centre on Social Inclusion and Health. | OSTLIN Piroska | Active | Details |