Title of the centre:
WHO Collaborating Centre for Reference & Research on Poliomyelitis
Director / Head:
Dr Javier Martin
National Institute for Biological Standards and Control
Blanche Lane, South Mimms
(44-1707) 641 295
(44-1707) 641 050
Date of Designation:
Terms of Reference:
- To provide definitive identification where appropriate of poliovirus isolates from different surveillance activities using monoclonal antibodies and/or molecular methods to differentiate wild, vaccine and vaccine-derived strains.
- To produce and distribute working reagents and International standards to be used in different poliovirus assays.
- To act as a resource for the development and use of training materials and to provide training sites.
- To perform research on the molecular biology of poliovirus in relation to the Global Polio Eradication Initiative (GPEI) and the immunization strategies before and after eradication is achieved.
- To organize and participate in collaborative studies to assess proposed standards, reference materials and methodologies or to answer specific research questions related to the GPEI providing appropriate information to WHO/HQ and Regional Offices.
- To provide independent technical expertise and advice for assessing the safety, potency, efficacy and QC of poliovaccines.
- To investigate and develop new and improved methodologies for the assessment of the safety of live-attenuated oral poliovaccine (OPV).
- To investigate and develop new and improved International standards and methodologies for the standardisation of poliovirus inactivated vaccine (IPV).
9. To take an active part in meetings of designated collaborating and reference laboratories organised by WHO.
- Health Technology (including laboratory services; but excluding blood safety)
Types of activity:
- Training and education
- Providing technical advise to WHO
Ower: 1.1 - Policy and technical support provided to Member States in order to maximize equitable access of all people to vaccines of assured quality, including new immunization product and technologies, and to integrate other essential child-health interventions with immunization.
Ower: 1.2 - Effective coordination and support provided in order to achieve certification of poliomyelitis eradication, and destruction , or appropriate containment, of polioviruses, leading to a simultaneous cessation of oral poliomyelitis vaccination globally.
Ower: 1.4 - Policy and technical support provided to Member States in order to enhance their capacity to carry out surveillance and monitoring of all communicable diseases of public health importance.
+41 22 79 12503
+45 45 33 66 80
Access to annual progress reports and the current workplan (this is accessible to WHO Staff Members only):
Link to eWork