Title of the centre:
WHO Collaborating Centre for Smallpox Vaccine
Director / Head:
Prof. dr. mrs M.C.J.P. Boog
Dr Willem Luytjes
Netherlands Vaccine Institute (NVI)
Ministry of Health, Welfare and Sport
P.O. Box 457, Antonie van Leeuwenhoeklaan 11
(31-30) 274 8563/7520
(31-20) 274 4439
Date of Designation:
Date of Discontinuation:
Terms of Reference:
- To hold vaccinia seed virus & reference materials required for the production, potency testing & quality control of smallpox vaccine. Make these materials available at the request of WHO.
- To distribute vaccinia seed virus & other reference materials on the advice & approval of WHO.
- To undertake arrangements for replenishing vaccinia seed stocks when necessary.
- To undertake collaborative activities to assess the quality & characteristics of vaccinia seed stocks.
- To test batches of smallpox vaccine from the WHO vaccine reserves according to agreed upon criteria & schedule within the designation period.
- To set up a smallpox vaccine information centre in which information on smallpox vaccine is collected & stored.
- To have trained and properly vaccinated personel available to carry out the tasks described in TOR 1-5.
- To underpin WHO with the logistics of emergency vaccination against smallpox.
Types of activity:
- Product development (guidelines; manual; methodologies; etc.)
- Information dissemination
WHO organization wide expected result:
1.4 - Policy and technical support provided to Member States in order to enhance their capacity to carry out surveillance and monitoring of all communicable diseases of public health importance.
1.7 - Member States and the international community equipped to detect, assess, respond to and cope with major epidemic and pandemic-prone diseases (e.g. influenza, meningitis, yellow fever, haemorrhagic fevers, plague and smallpox) through the development and implementation of tools, methodologies, practices, networks and partnerships for prevention, detection, preparedness and intervention.
1.8 - Regional and global capacity coordinated and made rapidly available to Member States for detection, verification, risk assessment and response to epidemics and other public health emergencies of international concern.
COSTA Alejandro Javier
+41 22 79 14965
+45 45 33 66 80
Access to annual progress reports and the current workplan (this is accessible to WHO Staff Members only):
Link to eWork