Effects of pulmonary re-expansion maneuver on patients receiving mechanical ventilation

• Register: REBEC
• Last refreshed on: 29 April 2013
• Main ID: RBR-268hqh
• Date of registration: 01/05/2012
• Primary sponsor: Hospital e Maternidade Celso Pierro - Brazil
• Public title: Effects of pulmonary re-expansion maneuver on patients receiving mechanical ventilation
• Scientific title: Effects of Manual Chest Compression and Descompression Maneuver on Lung Volumes, Capnography and Pulse Oximetry in Patients Receiving Mechanical Ventilation - :
• Date of first enrolment: 21/08/2010
• Target sample size: 65
• Recruitment status: data analysis completed
• URL: http://www.ensaiosclinicos.gov.br/rg/RBR-268hqh/
• Study design: Clinic trial, prospective, single arm.

Countries of recruitment

Brazil

Contacts

• Name: Fabiana Della Via
• Affiliation: Universidade Estadual de Campinas

• Name: Fabiana Della Via
• Affiliation: Universidade Estadual de Campinas

Key inclusion & exclusion criteria

Inclusion criteria: Age greater than 18 years
Patients on mechanical ventilation
Ramsay sedation scale between 4 and 6 levels
Hemodynamic stability
No osteoarticular lesions (rib fractures or unstable thorax).
Exclusion criteria: Intracranial hypertension > 30 mmHg
Pneumothorax
Hemodynamic instability with use of high doses of vasoactive drugs, dopamine and dobutamine > 5 µg/kg/min and noradrenalin > 0.5 µg /kg/min

Age minimum: 18Y
Age maximum: 100Y
Gender: -

Health Condition(s) or Problem(s) studied

Hospitalized patients in intensive care units (ICU) are prone to developing respiratory complications, particularly atelectasis and bronchopneumonia.
C08.381.730

Intervention(s)

After 24 hours of mechanical ventilation 65 patients were placed in supine position with the head of bed elevated to an angle of 30o and carried out a chest radiograph.
Thereafter they were submitted to bronchial hygiene according to the following protocol: manual chest compression and vibrations in the expiratory phase of respiratory cycle in the previous chest wall during 10 minutes and endotracheal suctioning with open system following to the instructions of the American Association of Respiratory Care.
After 30 minutes of bronchial hygiene was measured the first data collection prior to the maneuver and than 20 repetitions of MCCD were performed in 10 consecutive respiratory cycles in the right hemithorax and 10 repetitions in the left hemithorax. The variables were collected at 1, 5, 10, 15, 20, 25, 30, 35 and 40 minutes following the procedure.

Primary Outcome(s)

Reverse atelectasis after the application of the manual chest compression and decompression maneuver,
from the measurement of lung volumes following: inspiratory tidal volume (VTi), expiratory tidal volume (VTE), minute volume, and measurement of oxygen saturation (SpO2), capnography (Pet CO2).

Secondary Outcome(s)

Improvement in pulmonary volume
Improvement in pulse oximetry
Reduction occurred in expiratory CO2
No alteration occurred in heart rate and mean arterial pressure

Secondary ID(s)

(338/2008)

Source(s) of Monetary Support

Universidade Estadual de Campinas - Brazil

Fabiana Della Via - Brazil

Hospital e Maternidade Celso Pierro - Brazil

Secondary Sponsor(s)

Universidade Estadual de Campinas - Brazil