Atorvastastin and HIV associated immune activation

• Register: PACTR
• Last refreshed on: 29 April 2013
• Main ID: PACTR201301000445375
• Date of registration: 26/10/2012
• Primary sponsor: Damalie Nakanjako
• Public title: Atorvastastin and HIV associated immune activation
• Scientific title: Use of Atorvastatin among HAART-treated adults with suboptimal immune recovery in Uganda
• Date of first enrolment: 2012-12-10
• Target sample size: 30
• Recruitment status: Open to recruitment: actively recruiting participa
• URL: HTTP://www.pactr.org/ATMWeb/appmanager/atm/atmregistry?da=true&tno=PACTR201301000445375
• Study type: interventional
• Study design: Crossover: all participants receive all interventions in different sequence during study,; Randomised,; simple randomisation using a randomisation table created by a computer software program,; sealed opaque envelopes,

Countries of recruitment

South Africa

Contacts

• Name: Francis Codero
• Affiliation: Prin

• Name: Francis Codero
• Affiliation: Principal investigator

Key inclusion & exclusion criteria

Inclusion criteria: ASA I and II patients scheduled for lower limb orthopaedic surgery
Exclusion criteria: 1. Patient refusal
2. Patients `18years and b76years
3.Failure to reach the sub arachnoid space and converted to GA
4.Patients with contraindications to neuraxial anaesthesia
Puncture site infection
Hypovolemic shock
c. Coagulopathy
d. Sepsis
5. Patients with psychological / mental instability
6. Patients with known psychiatric condition
7. Patient involved in any other clinical studies


Age minimum: 18 Year
Age maximum: 75 Year
Gender: Both

Health Condition(s) or Problem(s) studied

null

Primary Outcome(s)

Time to first request of analgesia following surgery

Source(s) of Monetary Support

Aga Khan University Hospital