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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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PACTR |
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Last refreshed on:
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29 April 2013 |
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Main ID: |
PACTR201109000317141 |
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Date of registration:
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20/09/2011 |
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Primary sponsor: |
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Public title:
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effect of blood transfusion on oxygen extraction ratio [pharmacodynamic study; retrospectively registered]
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Scientific title:
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the effect of blood transfusion on oxygen extraction ratio in adult patients admitted to the general intensive care unit at a tertiary level teaching hospital: a quasi experimental study |
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Date of first enrolment:
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2011-07-01 |
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Target sample size:
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58 |
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Recruitment status: |
Open to recruitment: actively recruiting participa |
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URL:
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HTTP://www.pactr.org/ATMWeb/appmanager/atm/atmregistry?da=true&tno=PACTR201109000317141 |
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Study type:
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interventional |
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Study design:
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Single group: all participants receive same intervention throughout study,
Non-randomised,
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Countries of recruitment
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South Africa
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Contacts
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Name:
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vitalis
mung'ayi |
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Address:
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3rd parklands avenue
254
nairobi
Kenya |
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Telephone:
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+254733635554 |
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Email:
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mung'ayi.vitalis@aku.edu |
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Affiliation:
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faculty |
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Name:
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thikra
sharif |
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Address:
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3rd parklands avenue
254
nairobi
Kenya |
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Telephone:
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+254722385127 |
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Email:
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pain.management@aku.edu |
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Affiliation:
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faculty/supervisor |
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Key inclusion & exclusion criteria
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Inclusion criteria: icu patients undergoing blood transfusion(packed cells or whole blood)
age above 18 years
mean arteria pressure of at least 65mmHg
urine output of at least 0.5mls/kg/hr OR patients with endstage renal disease on renal replacement therapy
Exclusion criteria: age below 18 years
mean arterial pressure below 65mmHg
urine output less than 0.5mls/kg/hr in the absence of chronic kidney disease
ongoing bleeding as the indication for transfusion
heart failure
carbon monoxide poisoning
shock of any origin
Age minimum:
18 Year
Age maximum:
90 Year
Gender:
Both
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Health Condition(s) or Problem(s) studied
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anaemia in critical care
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Primary Outcome(s)
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the change in oxygen extraction ratio after blood transfusion
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Secondary Outcome(s)
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to determine the relationship between change in hemoglobin concentration and change in oxygen extraction ratio
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Source(s) of Monetary Support
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aga khan university PGME
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