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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: Netherlands Trial Register
Last refreshed on: 28 April 2013
Main ID:  NTR994
Date of registration: 07/06/2007
Primary sponsor: Academic Medical Center (AMC), Department of Surgery
Public title: The Anal Fistula Plug versus the mucosal flap advancement for the treatment of Perianal Fistulas.
Scientific title: The Anal Fistula Plug versus the mucosal flap advancement for the treatment of Perianal Fistulas. - PLUG
Date of first enrolment: 1/10/2006
Target sample size: 60
Recruitment status: complete
URL:  http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=994
Study type:  intervention
Study design:  Randomised: Yes; Masking: Double; Control: Active; Group: Parallel; Type: 2 or more arms, randomized  
Countries of recruitment
The Netherlands
Contacts
Name: J.F.M.   Slors
Address:  AMC, Afd. Chirurgie, Meibergdreef 9 1105 AZ Amsterdam The Netherlands
Telephone: +3120-5669111
Email: j.f.slors@amc.uva.nl
Affiliation: 
Name: J.F.M.   Slors
Address:  AMC, Afd. Chirurgie, Meibergdreef 9 1105 AZ Amsterdam The Netherlands
Telephone: +3120-5669111
Email: j.f.slors@amc.uva.nl
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: 1. High anorectal fistula of cryptoglandular origin (transsfincteric, upper 2/3 of the sfinctercomplex which is confined by the puborectal sling and the end of the anal canal);

2. Informed consent.

Exclusion criteria: 1. Age<18 years;

2. HIV-positive;

3. Crohn´s disease;

4. Malignant cause;

5. Tuberculosis;

6. Hidradenitis suppurativa;

7. Pilonidal sinus disease;

8. No internal opening found during surgery.


Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Perianal fistula

Intervention(s)
Installation of the anal fistula plug.
Primary Outcome(s)
1. Anorectal fistula closure rate;

2. Continence.
Secondary Outcome(s)
1. Morbidity;

2. Post-operative pain;

3. Sick leave;

4. Quality of life.
Secondary ID(s)
ISRCTN97376902
N/A
Source(s) of Monetary Support
Academic Medical Center (AMC), Department of Surgery
Secondary Sponsor(s)
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