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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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Netherlands Trial Register |
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Last refreshed on:
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28 April 2013 |
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Main ID: |
NTR971 |
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Date of registration:
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15/05/2007 |
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Primary sponsor: |
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Public title:
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Effect of breakfast cereals compared with corn flakes on blood glucose, gastric emptying and satiety in healthy subjects.
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Scientific title:
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Effect of ß-glucan breakfast cereals compared with corn flakes on postprandial blood glucose, gastric emptying and satiety in healthy subjects: a randomized crossover blinded trial. - N/A |
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Date of first enrolment:
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1/4/2003 |
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Target sample size:
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12 |
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Recruitment status: |
complete |
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URL:
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http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=971 |
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Study type:
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intervention |
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Study design:
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Randomised: Yes; Masking: Double; Control: Not applicable; Group: Crossover; Type: 2 or more arms, randomized
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Countries of recruitment
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The Netherlands
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Contacts
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Name:
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Joanna
Hlebowicz |
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Address:
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Dept. of Medicine, Malmö University Hospital, Ingång 35
205 02
Malmö
Sweden |
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Telephone:
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+46-40-331000 |
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Email:
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Joanna.Hlebowicz@skane.se |
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Affiliation:
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Name:
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Joanna
Hlebowicz |
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Address:
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Dept. of Medicine, Malmö University Hospital, Ingång 35
205 02
Malmö
Sweden |
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Telephone:
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+46-40-331000 |
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Email:
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Joanna.Hlebowicz@skane.se |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: Helthy subjects without symptoms or a prior history of gastrointestinal disease, abdominal surgery or diabetes mellitus were included in the study.
Exclusion criteria: 1. Diabetes mellitus;
2. prior abdominal surgery;
3. symtoms of gastrointestinal disease;
4. Obesity.
Age minimum:
Age maximum:
Gender:
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Health Condition(s) or Problem(s) studied
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Beta-glucan, Gastric emptying, Postprandial blood glucose, Healthy subjects
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Intervention(s)
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Twelve healthy subjects were assessed using a randomized crossover blinded trial. The subjects were examined after an 8 hours fast and assessment of normal fasting blood glucose level. Gastric emptying rate was calculated as the percentage change in the antral cross-sectional area 15 and 90 minutes after ingestion of vanilla yoghurt with flakes containing 4 g beta-glucan (GER1) or vanilla yoghurt with Kellogg´s cornflakes (GER2). Significant differences were evaluated with Wilcoxon t-test.
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Primary Outcome(s)
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The ß-glucan effect on the rate of gastric emptying was statistically not significant compared with cornflakes. Consumption of ß-glucan lowered the postprandial glucose response significant (p<0.05).
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Secondary Outcome(s)
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The effect of ß-glucan on satiety was not statistically significant.
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Secondary ID(s)
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ISRCTN90535566
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Source(s) of Monetary Support
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Skånemejerier, Malmö, Sweden
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