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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: Netherlands Trial Register
Last refreshed on: 28 April 2013
Main ID:  NTR968
Date of registration: 10/05/2007
Primary sponsor: University Medical Center Utrecht (UMCU)
Public title: Effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections.
Scientific title: Effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections. - NOA (Nederlands Onderzoek Adenotomie)
Date of first enrolment: 1/4/2007
Target sample size: 110
Recruitment status: complete
URL:  http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=968
Study type:  intervention
Study design:  Randomised: Yes; Masking: None; Control: Active; Group: Parallel; Type: [default]  
Countries of recruitment
The Netherlands
Contacts
Name: Anne G.M.  Schilder
Address:  University Medical Center Utrecht Wilhelmina Children's Hospital Department of Otorhinolaryngology PO Box 85090 3508 AB Utrecht The Netherlands
Telephone: +31 (0)30 2504004
Email: A.Schilder@umcutrecht.nl
Affiliation: 
Name: Anne G.M.  Schilder
Address:  University Medical Center Utrecht Wilhelmina Children's Hospital Department of Otorhinolaryngology PO Box 85090 3508 AB Utrecht The Netherlands
Telephone: +31 (0)30 2504004
Email: A.Schilder@umcutrecht.nl
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: Children aged 1-6 years selected for adenoidectomy primarily because of recurrent upper respiratory tract infections (common colds and rhinosinusitis).
Exclusion criteria: 1. Age younger than 1 year or older than 6 years;
2. Previous adenoidectomy or adenotonsillectomy;
3. Tympanostomy tubes present;
4. Selected for adenoidectomy combined with tympanostomy tubes;
5. Down?s syndrome;
6. Craniofacial malformations (eg.cleft lip or palate)


Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Children, Randomised study, Adenoidectomy, Upper respiratory tract infection, Common cold, Rhinosinusitis

Intervention(s)
Adenoidectomy within 6 weeks versus watchful waiting.
Primary Outcome(s)
Upper respiratory tract infection with or without fever (38°C or higher)

Secondary Outcome(s)
1. Acute otitis media and otitis media with effusion episodes;
2. Exhaled nitric oxide;
3. Nasopharyngeal flora;
4. Health related quality of life;
5. Cost-effectiveness
Secondary ID(s)
ISRCTN03720485
Source(s) of Monetary Support
ZON-MW, The Netherlands Organization for Health Research and Development
Secondary Sponsor(s)
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