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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: Netherlands Trial Register
Last refreshed on: 28 April 2013
Main ID:  NTR941
Date of registration: 27/03/2007
Primary sponsor: Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital (NKI AVL)
Public title: Prevention of lymphedema by therapeutic elastic compression hoses; treatment efficacy.
Scientific title: The efficacy of therapeutic compression hoses for prevention of lymphedema after inguinal lymph node dissection in cancer patients ? a randomized controlled trial. - PROTECT
Date of first enrolment: 1/10/2006
Target sample size: 80
Recruitment status: complete
URL:  http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=941
Study type:  intervention
Study design:  Randomised: Yes; Masking: None; Control: Active; Group: Parallel; Type: 2 or more arms, randomized  
Countries of recruitment
The Netherlands
Contacts
Name: M.M.  Stuiver
Address:  The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Dpt of Physiotherapy, Plesmanlaan 121 1066 CX Amsterdam The Netherlands
Telephone: +31 20-5122586
Email: m.stuiver@nki.nl
Affiliation: 
Name: M.M.  Stuiver
Address:  The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Dpt of Physiotherapy, Plesmanlaan 121 1066 CX Amsterdam The Netherlands
Telephone: +31 20-5122586
Email: m.stuiver@nki.nl
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: 1. 18 years or older;

2. Inguinal lymphnode dissection because of metastases of melanoma or urogenital tumour.

Exclusion criteria: 1. Deep venous thrombosis;

2. Manifest lymphedema or episodes of lymphedema in the past;

3. Isolated limb perfusion treatment;

4. Oedema as a result of venous insufficiency;

5. Psychiatric disorders;

6. Lacking basic proficiency in dutch.


Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Inguinal lymph node dissection, Lymphedema, Elastic stockings

Intervention(s)
Therapeutic elastic compression hose for a period of 6 months, in addition to standard regimen of early ambulation and patient education.
Primary Outcome(s)
Incidence of lymphedema (survival without lymphedema).
Secondary Outcome(s)
1. Early surgical complications (wound breakdown, lymphocele formation, wound infection);

2. Genital oedema;

3. Health related quality of life;

4. Body image;

5. Ccompliance to usage of the hose;

6. Use of professional homecare;

7. Lymphedema requiring treatment.
Secondary ID(s)
ISRCTN23026635
N/A
Source(s) of Monetary Support
Netherlands Cancer Institute - Antoni van Leeuwenhoek
Secondary Sponsor(s)
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