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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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Netherlands Trial Register |
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Last refreshed on:
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28 April 2013 |
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Main ID: |
NTR938 |
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Date of registration:
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12/03/2007 |
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Primary sponsor: |
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Public title:
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Subclinical cerebellar dysfunction in patients with migraine.
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Scientific title:
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Subclinical cerebellar dysfunction in patients with migraine. - N/A |
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Date of first enrolment:
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1/3/2007 |
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Target sample size:
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60 |
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Recruitment status: |
complete |
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URL:
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http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=938 |
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Study type:
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intervention |
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Study design:
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Randomised: No; Masking: None; Control: Not applicable; Group: Parallel; Type: 2 or more arms, non-randomized
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Countries of recruitment
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The Netherlands
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Contacts
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Name:
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W.
Brekelmans |
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Address:
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Leiden University Medical Center (LUMC)
P.O. Box 9600, Albinusdreef 2
2300 RC
Leiden
The Netherlands |
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Telephone:
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+ 31 71-5261730 |
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Email:
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w.brekelmans@umail.leidenuniv.nl |
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Affiliation:
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Name:
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W.
Brekelmans |
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Address:
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Leiden University Medical Center (LUMC)
P.O. Box 9600, Albinusdreef 2
2300 RC
Leiden
The Netherlands |
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Telephone:
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+ 31 71-5261730 |
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Email:
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w.brekelmans@umail.leidenuniv.nl |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Patients with migraine and aura with minimal 6 attacks a year (2 with aura);
2. Healthy volunteers without migraine;
3. Patients with a cerebellar degenerative diseases.
Exclusion criteria: For the migrainepatients and healthy controls:
1. Neurologic diseases in which the function of cerebellum is disturbed;
2. The use of medicines/drugs which have influence on the coordination 24 hours before taking part of this examination.
Age minimum:
Age maximum:
Gender:
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Health Condition(s) or Problem(s) studied
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Migraine, Eyeblink, Cerebellum, Sway test
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Intervention(s)
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The difference in the conditioning, between migraineurs and healthy volunteers,
is measured by using the eyeblinker. The technique is called the chip-MDMT
(Magnetic Distant Measurement Technique). A magnet will be placed on the right eyelid. A sensor will be placed below the right eye. So the length, the power and the time of each blink is measured. The test will consist of 8 trials of 6 minutes. A conditioned respons will be generated by using airpuffs and tones.
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Primary Outcome(s)
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The conditioning as measured with eyeblink between migrainepatients and controls.
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Secondary Outcome(s)
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1. The sensitivity of trigeminus system by migrainepatients compared with controls.
Do the results of the disturbed conditioned corresponds to a coordinationdisorder measured by the sway-test?;
2. The relations between the contols, the migrainepatients and the patients with a degenerative disease.
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Secondary ID(s)
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ISRCTN94004433
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N/A
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Source(s) of Monetary Support
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Leiden University Medical Center (LUMC), Department of Neurology
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