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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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Netherlands Trial Register |
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Last refreshed on:
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28 April 2013 |
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Main ID: |
NTR875 |
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Date of registration:
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19/01/2007 |
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Primary sponsor: |
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Public title:
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The pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care.
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Scientific title:
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The pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care. - Nimodipine subarachnoidal hemorrhage ICU |
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Date of first enrolment:
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1/12/2006 |
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Target sample size:
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12 |
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Recruitment status: |
complete |
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URL:
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http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=875 |
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Study type:
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intervention |
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Study design:
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Randomised: No; Masking: None; Control: Not applicable; Group: [default]; Type: Single arm
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Countries of recruitment
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The Netherlands
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Contacts
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Name:
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B.M.
Kors |
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Address:
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VU medisch centrum
Afdeling intensive care volwassenen
Boelelaan 1117
1081 HV
Amsterdam
The Netherlands |
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Telephone:
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+ 31 20 4443900 |
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Email:
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bm.kors@vumc.nl |
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Affiliation:
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Name:
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A.R.J
Girbes |
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Address:
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VU medisch centrum
afdeling intensive care volwassenen, Boelelaan 1117
1081 HV
Alkmaar
The Netherlands |
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Telephone:
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Email:
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. All patients admitted on the ICU with subarachnoidal hemorrhage (SAB), treated according to our SAB-protocol;
2. Adults aged 18 - 70 years old.
Exclusion criteria: 1. Pregnancy;
2. Expected mortality < 24 hours;
3. Severe hepatic function disorders;
4. Use of medication with know interaction in relation to nimodipine.
Age minimum:
Age maximum:
Gender:
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Health Condition(s) or Problem(s) studied
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Subarachnoid hemorrhage (SAH), Intensive care
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Intervention(s)
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Bloodsamples according to strict time protocol during treatment.
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Primary Outcome(s)
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1. Pharmacokinetics of nimodipine in this specific group of patients;
2. Variability of bio-availability of orally administred nimodipine.
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Secondary ID(s)
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ISRCTN45381163
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N/A
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Source(s) of Monetary Support
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VU University Medical Center, Department of Intensive Care
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