The use of narrow band imaging versus conventional colonoscopy for the detection of dysplasia and cancer in patients with longstanding ulcerative colitis. A randomized cross-over study.

• Register: Netherlands Trial Register
• Last refreshed on: 28 April 2013
• Main ID: NTR853
• Date of registration: 27/12/2006
• Primary sponsor: Academic Medical Center (AMC)
• Public title: The use of narrow band imaging versus conventional colonoscopy for the detection of dysplasia and cancer in patients with longstanding ulcerative colitis. A randomized cross-over study.
• Scientific title: Narrow band imaging for neoplasia detection in patients with longstanding ulcerative colitis. - EVE II study
• Date of first enrolment: 13/12/2006
• Target sample size: 49
• Recruitment status: recruiting
• URL: http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=853
• Study type: intervention
• Study design: Randomised: Yes; Masking: None; Control: Active; Group: Crossover; Type: -

Countries of recruitment

The Netherlands

Contacts

• Name: Evelien Dekker

• Name: Evelien Dekker

Key inclusion & exclusion criteria

Inclusion criteria: 1. Objective diagnosis of UC (histologically and/or endoscopically);
2. Extensive UC (proximal to splenic flexure);
3. Disease duration > 8 years;
4. Inactive disease (Truelove Witts Index<2);
5. Informed consent.
Exclusion criteria: 1. Age < 18 years;
2. Non correctable coagulopathy.

Age minimum:
Age maximum:
Gender:

Health Condition(s) or Problem(s) studied

Emollients

Intervention(s)

NBI-Colonoscopy and WLE-colonoscopy.

Primary Outcome(s)

Number of patients with detected neoplasia.

Secondary Outcome(s)

1. Number of neoplastic lesions;
2. Pit pattern classification (Kudo) of neoplastic lesions;
3. Vascular pattern description of neoplastic lesions.

Secondary ID(s)

ISRCTN56671833

N/A

Source(s) of Monetary Support

Academic Medical Center (AMC)