World Health Organization site
Skip Navigation Links

Main
Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: Netherlands Trial Register
Last refreshed on: 28 April 2013
Main ID:  NTR820
Date of registration: 21/11/2006
Primary sponsor: Trimbos-institute - Netherlands Institute of Mental Health and Addiction
Public title: Collaborative Care: Depression Initiative in Primary care.
Scientific title: A Collaborative Care framework including PST and an Antidepressant Treatment Algorithm for treatment of Major Depressive Disorder in primary care; a Cluster Randomized Trial. - CC: DIP
Date of first enrolment: 1/12/2006
Target sample size: 240
Recruitment status: recruiting
URL:  http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=820
Study type:  intervention
Study design:  Randomised: Yes; Masking: Single; Control: Active; Group: Parallel; Type: [default]  
Countries of recruitment
The Netherlands
Contacts
Name: C.M.  Feltz-Cornelis, van der
Address:  Trimbos-institute - Netherlands Institute of Mental Health and Addiction, Department of Diagnosis en Treatment, P.O. Box 725, Da Costakade 45 3500 AS Utrecht The Netherlands
Telephone:
Email: cfeltz@trimbos.nl
Affiliation: 
Name: F.J.  Jong de
Address:  Trimbos-instituut, Netherlands institute of Mental Health and Addiction, Da Costakade 45, P.O. Box 725 3500 AS Utrecht The Netherlands
Telephone: +31 (0)30 2971185
Email: mijff@trimbos.nl
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: The aim is to include patients who are diagnosed with major depressive disorder and who dysfunction due to the depressive disorder (i.e. loss of role in daily life).
Exclusion criteria: Patients are excluded from the study if they are suicidal, psychotic or suffering from dementia, have insufficient knowledge of Dutch to fill in the questionnaires, are addicted to drugs or alcohol, already receive psychiatric treatment and/or are less than 18 years old.

Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Depressive disorders

Intervention(s)
The collaborative care approach includes care management, contracting, adherence improving strategies, manual guided self help and lifestyle interventions, Problem Solving Treatment, and an antidepressant treatment algorithm; the treatment plan is set based on patient preferences.
Primary Outcome(s)
The primary outcome measure is response. Secondary outcome measures are remission as measured by the PHQ9 and IDS-SR, effect of chronic physical illness as an effect modifier, and cost-effectiveness as measured with the TiC-P, EQ-5D and the SF-36.
Secondary Outcome(s)
Secondary outcome measures are remission, effect of chronic physical illness and cost-effectiveness.
Secondary ID(s)
ISRCTN15266438
N/A
Source(s) of Monetary Support
Foundation Reserves Voormalige Vrijwillige Ziekenfondsverzekering (RVVZ)
Secondary Sponsor(s)
Disclaimer: Trials posted on this search portal are not endorsed by WHO, but are provided as a service to our users. In no event shall the World Health Organization be liable for any damages arising from the use of the information linked to in this section. None of the information obtained through use of the search portal should in any way be used in clinical care without consulting a physician or licensed health professional. WHO is not responsible for the accuracy, completeness and/or use made of the content displayed for any trial record.
Copyright - World Health Organization - Version 3.1 - Version history