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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: Netherlands Trial Register
Last refreshed on: 27 May 2013
Main ID:  NTR818
Date of registration: 21/11/2006
Primary sponsor: Trimbos-institute - Netherlands Institute of Mental Health and Addiction
Public title: Collaborative Care: Depression Initative in the Medical Setting.
Scientific title: Cost-effectiveness of collaborative care for chronic medically ill patients with comorbid depressive disorder in the general hospital setting. - CC: DIM
Date of first enrolment: 1/12/2006
Target sample size: 126
Recruitment status: pending
URL:  http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=818
Study type:  intervention
Study design:  Randomised: Yes; Masking: Single; Control: Active; Group: Parallel; Type: -  
Countries of recruitment
The Netherlands
Contacts
Name: C.M.  Feltz-Cornelis, van der
Address:  Trimbos-institute - Netherlands Institute of Mental Health and Addiction, Department of Diagnosis en Treatment, P.O. Box 725, Da Costakade 45 3500 AS Utrecht The Netherlands
Telephone:
Email: cfeltz@trimbos.nl
Affiliation: 
Name: Eva  Horn
Address:  Trimbos-instituut / Netherlands institute of Mental Health and Addiction, Da Costakade 45, P.O. Box 725 3500 AS Utrecht The Netherlands
Telephone: +31 (0)30 2959303
Email: ehorn@trimbos.nl
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: All patients of the Onze Lieve Vrouwe Gasthuis visiting the participating outpatient clinics (diabetes, cardiology, HIV, and part of lung medicine [patients with COPD]) and who already have a diagnosis specified in their file. Patients are included in the study if a cut off score of 15 (moderate to severe depressive disorder) is reached on a the PHQ-9, which measures depression severity. The symptoms have to be present for at least six weeks or have to cause marked dysfunctioning (e.g. problems at work, housekeeping).
Exclusion criteria: Suicidality (in case of a high risk for suicide, patients will be referred.)

(Concerning the following criteria a suggestion is given to the patients concerning a different kind of help:)
-Psychotic
-Suffering from dementia or delirium
-Insufficient knowledge of the Dutch language to fill in questionnaires
-Serious mental impairment
-Alcohol or drug addiction
-Already receiving psychiatric treatment
-Pregnancy
-Bipolar disorder

Concerning HIV patients:
-Organic psychosyndrome
-Personality change
-In terminal phase


Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Comorbid depressive disorder

Intervention(s)
A treatment of depression fit in the collaborative care model with problem solving treatment, an antidepressant algorithm, contracting, care management, and a manual guided self-help depression for chronically ill patients.
Primary Outcome(s)
Severity of depressive symptoms.
Secondary Outcome(s)
The cost-utility of collaborative care compared to CAU.
Secondary ID(s)
ISRCTN95575369
N/A
Source(s) of Monetary Support
Onze Lieve Vrouwe Gasthuis (OLVG), Foundation Reserves Voormalige Vrijwillige Ziekenfondsverzekering (RVVZ)
Secondary Sponsor(s)
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