World Health Organization site
Skip Navigation Links

Main
Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: Netherlands Trial Register
Last refreshed on: 28 April 2013
Main ID:  NTR2856
Date of registration: 17/04/2011
Primary sponsor: Máxima Medical Center
Public title: Primary treatment of vaginal prolapse: Pessary use versus prolapse surgery.
Scientific title: Primary treatment of vaginal prolapse: Pessary use versus prolapse surgery. - ROK
Date of first enrolment: 1/1/2010
Target sample size: 80
Recruitment status: recruiting
URL:  http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2856
Study type:  intervention
Study design:  Randomised: Yes; Masking: None; Control: Active; Group: Parallel; Type: 2 or more arms, randomized  
Countries of recruitment
The Netherlands
Contacts
Name: A.L.W.M.  Coolen
Address:  Polikliniek gynaecologie, tav A.Coolen Postbus 7777 5500 MB Veldhoven The Netherlands
Telephone:
Email: a.coolen@mmc.nl
Affiliation: 
Name: A.L.W.M.  Coolen
Address:  Polikliniek gynaecologie, tav A.Coolen Postbus 7777 5500 MB Veldhoven The Netherlands
Telephone:
Email: a.coolen@mmc.nl
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: 1. POP-Q stage grade 2-4 (POP-Q according to ICS);

2. Eligible for pessary treatment and prolapse surgery.

Exclusion criteria: 1. Isolated rectocele;

2. Previous prolapse treatment;

3. Previous treatment against urine incontinence.


Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Pessary, Prolapse, Prolapse surgery

Intervention(s)
Pessary:

1. Portex;

2. Falk.



Prolapse surgery:

1. Vaginal hysterectomy;

2. Anterior colporrhaphy;

3. Posterriorcolporrhaphy;

4. A combination of above-mentioned surgical treatments;

5. A combination of above-mentioned surgical treatments including MESH material.
Primary Outcome(s)
The primary outcome will be disease specific quality of life, which will be evaluated by using the urogenital distress inventory (UDI).
Secondary Outcome(s)
1. General quality of life and patients satisfaction rate. Both will be evaluated by using a validated questionnaire (werkgroepbekkenbodem, eurqol, SF-36);

2. Successful continuous pessary treatment;

3. Anatomical result. Evaluated through pelvic examination according to the recommendations of the ICS.
Secondary ID(s)
0826
Source(s) of Monetary Support
Maxima Medical Center
Secondary Sponsor(s)
Disclaimer: Trials posted on this search portal are not endorsed by WHO, but are provided as a service to our users. In no event shall the World Health Organization be liable for any damages arising from the use of the information linked to in this section. None of the information obtained through use of the search portal should in any way be used in clinical care without consulting a physician or licensed health professional. WHO is not responsible for the accuracy, completeness and/or use made of the content displayed for any trial record.
Copyright - World Health Organization - Version 3.1 - Version history