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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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Netherlands Trial Register |
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Last refreshed on:
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28 April 2013 |
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Main ID: |
NTR2490 |
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Date of registration:
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01/09/2010 |
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Primary sponsor: |
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Public title:
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Strategy to recognize and initiate treatment of chronic heart failure (STRETCH).
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Scientific title:
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A combined diagnostic-therapeutic strategy to optimize management of patients with previously unrecognized heart failure in primary care. - STRETCH |
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Date of first enrolment:
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1/10/2010 |
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Target sample size:
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1500 |
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Recruitment status: |
pending |
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URL:
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http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2490 |
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Study type:
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intervention |
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Study design:
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Randomised: Yes; Masking: Single; Control: Active; Group: Parallel; Type: 2 or more arms, randomized
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Countries of recruitment
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The Netherlands
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Contacts
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Name:
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F.H.
Rutten |
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Address:
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Utrecht
The Netherlands |
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Telephone:
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+31 (0)88 7568051 |
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Email:
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F.H.Rutten@umcutrecht.nl |
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Affiliation:
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Name:
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Evelien E.S.
Riet, van |
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Address:
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Stratenum 5.143
3508 GA
Utrecht
The Netherlands |
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Telephone:
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+31 (0)6 0887568363 |
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Email:
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E.E.S.vanRiet@umcutrecht.nl |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Age 65 years or over;
2. Shortness of breath as reason for GP contact in the previous 12 months.
Exclusion criteria: 1. Already established heart failure, that is a diagnosis of heart failure confirmed by the cardiologist with echocardiography;
2. A life expectancy shorter than 6 months;
3. Not being able to give informed consent.
Age minimum:
Age maximum:
Gender:
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Health Condition(s) or Problem(s) studied
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Heart failure
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Intervention(s)
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Training of general practitioners in up-titration of heart failure medication. General practitioners in the intervention group will receive a single training of 2 hours from a cardiologist. The uptitrationschema of ACE-inhibitors and betablockers (based on the newest version of the NHG-standard 'Heartfailure') will be discussed and considered are the unwanted effects, interactions and contra-indications. Practical examples are being used.
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Primary Outcome(s)
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The primary outcome of the diagnostic part of our combined diagnostic-therapeutic strategy is:
1. Prevalence of 'systolic' and 'diastolic' heart failure in elderly who presented to the general practitioner with shortness of breath on exertion.
The primary outcomes of the therapeutic part of our combined diagnostic-therapeutic strategy are:
1. Differences in prescription of ACE-inhibitors and beta-blockers between the intervention and control group after 6 months follow-up;
2. Differences in quality of life between patients in the two groups after 6 months follow-up.
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Secondary Outcome(s)
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1. Differences in heart failure related doctor-appointments and hospitalization rates between the intervention and control group during 6 months follow-up;
2. Cost-effectiveness of the implemented diagnostic-therapeutic strategy.
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Source(s) of Monetary Support
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Netherlands Heart Foundation (NHS, Nederlandse Hartstichting)
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