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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Last refreshed on: 17 October 2012
Main ID:  NCT01213706
Date of registration: 01/10/2010
Primary sponsor: University of Miami
Public title: Effect of Whole Body Periodic Acceleration on Airway Endothelial Function
Scientific title: Effect of Whole Body Periodic Acceleration on Airway Endothelial Function in Healthy Smokers, Non-smokers and Asmathics
Date of first enrolment: October 2009
Target sample size: 55
Recruitment status: Recruiting
Study type:  Interventional
Study design:  Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment  
Countries of recruitment
Key inclusion & exclusion criteria

Inclusion Criteria:

15 healthy never-smokers, 15 smokers (> than 1 year smoke history) and 15 never-smokers
asmathics; FEV1 > 80% (except for asmathics subjets)

Exclusion Criteria:

Women of childbearing potential who do not accepted birth control measures; pregnant and
breast feeding; cardiovascular disease or use of cardiovascular drugs; respiratory
infection during the 4 weeks preceding the study; use of inhaled or systemic
glucocorticoids, leukotriene modifiers or theophyllines in asmathics; FEV1 < 80% on the
screening day (excepted for asmathics subjets)

Age minimum: 20 Years
Age maximum: 65 Years
Gender: Both
Health Condition(s) or Problem(s) studied
Healthy Control
Device: Sham WBPA
Device: Whole Body Periodic Acceleration (WBPA)
Primary Outcome(s)
Airway Blood Flow changes [Time Frame: Qaw post minus Qaw pre WBPA treatment]
Secondary Outcome(s)
Nitric Oxide (NO) variation [Time Frame: NO post minus NO pre WBPA treatment]
Secondary ID(s)
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
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