Effect of Whole Body Periodic Acceleration on Airway Endothelial Function

• Register: ClinicalTrials.gov
• Last refreshed on: 19 October 2017
• Main ID: NCT01213706
• Date of registration: 01/10/2010
• Prospective Registration: No
• Primary sponsor: University of Miami
• Public title: Effect of Whole Body Periodic Acceleration on Airway Endothelial Function
• Scientific title: Effect of Whole Body Periodic Acceleration on Airway Endothelial Function in Healthy Smokers, Non-smokers and Asthmatics
• Date of first enrolment: October 2009
• Target sample size: 45
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT01213706
• Study type: Interventional
• Phase: N/A

Countries of recruitment

United States

Contacts

• Name: Adam Wanner, MD
• Affiliation: University of Miami

Key inclusion & exclusion criteria

Inclusion Criteria:

15 healthy never-smokers, 15 smokers (> than 1 year smoke history) and 15 never-smokers
asthmatics; FEV1 > 80% (except for asthmatics subjets)

Exclusion Criteria:

Women of childbearing potential who do not accepted birth control measures; pregnant and
breast feeding; cardiovascular disease or use of cardiovascular drugs; respiratory
infection during the 4 weeks preceding the study; use of inhaled or systemic
glucocorticoids, leukotriene modifiers or theophyllines in asthmatics; FEV1 < 80% on the
screening day (excepted for asthmatics subjets)



Age minimum: 20 Years
Age maximum: 65 Years
Gender: All

Health Condition(s) or Problem(s) studied

Asthma

Healthy

Smokers

Intervention(s)

Device: Whole Body Periodic Acceleration (WBPA)

Device: Sham WBPA

Primary Outcome(s)

Airway Blood Flow Response to Albuterol [Time Frame: Qaw post minus Qaw pre albuterol after WBPA or Sham WBPA]

Secondary ID(s)

20090748

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Results

• Results available: Yes
• Date Posted: 12/09/2014
• URL: https://clinicaltrials.gov/ct2/show/results/NCT01213706