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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT01196832 |
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Date of registration:
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01/06/2010 |
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Primary sponsor: |
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Public title:
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Role of Fibrocytes in Chronic Obstructive Pulmonary Disease
FIREBROB |
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Scientific title:
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Role of Fibrocytes in the Bronchial Remodeling of Chronic Obstructive Pulmonary Disease |
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Date of first enrolment:
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March 2011 |
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Target sample size:
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160 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT01196832 |
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Study type:
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Observational |
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Study design:
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Observational Model: Case Control, Time Perspective: Prospective
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Countries of recruitment
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France
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Contacts
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Name:
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Patrick BERGER, PUPH |
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Address:
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Telephone:
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(0)5 57 65 65 13 |
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Email:
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Affiliation:
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Name:
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Patrick BERGER, PUPH |
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Address:
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Telephone:
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(0)5 57 65 65 13 |
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Email:
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Affiliation:
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Name:
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Patrick BERGER, PUPH |
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Address:
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Telephone:
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Email:
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Affiliation:
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University Hospital Bordeaux (France) |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Patients: diagnostic of Chronic obstructive pulmonary disease (COPD) exacerbation.
- Control group: subjects without any history of lung disease and with normal lung
function testing. Subjects will be separated in 2 sub-groups according to smoking
history (Never smokers, smokers (former or current) and paired to patients according
to age and sex.
- Written informed consent
Exclusion Criteria:
- Subject without any social security or health insurance
- Asthma, lung fibrosis or idiopathic pulmonary hypertension
- Chronic viral infections (hepatitis, HIV)
Age minimum:
40 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Chronic Obstructive Pulmonary Disease
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Intervention(s)
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Procedure: blood sample
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Procedure: Clinical and functional evaluation
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Primary Outcome(s)
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Number of circulating blood fibrocytes
[Time Frame: 2 months]
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Number of circulating blood fibrocytes
[Time Frame: Day 1]
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Secondary Outcome(s)
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Characterization of fibrocytes
[Time Frame: Day 1 and at 2 months]
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Chemotactism of blood fibrocytes
[Time Frame: Day 1 and at 2 months]
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Differenciation of blood fibrocytes
[Time Frame: Day 1 and at 2 months]
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Secondary ID(s)
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CHUBX 2010/05
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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