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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 17 October 2012
Main ID:  NCT01100788
Date of registration: 05/03/2010
Primary sponsor: University of Minnesota - Clinical and Translational Science Institute
Public title: Satiety Response of Short Chain Fructooligosaccharide
Scientific title: Satiety Response of Short Chain Fructooligosaccharide
Date of first enrolment: March 2009
Target sample size: 20
Recruitment status: Completed
URL:  http://clinicaltrials.gov/show/NCT01100788
Study type:  Interventional
Study design:  Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention  
Countries of recruitment
United States
Contacts
Name:   Joanne Slavin
Address: 
Telephone:
Email:
Affiliation:  University of Minnesota - Clinical and Translational Science Institute
Key inclusion & exclusion criteria

Inclusion Criteria:

- Healthy men and women

- Age 18-64 years

- Non-smoking

- Not taking medication

- Non-dieting (weight stable in prior 3 months)

- BMI 18-27

- English literacy

Exclusion Criteria:

- Do not regularly consume breakfast

- Food allergies to ingredients found in study products

- BMI <18 or >27

- Diagnosed cardiovascular, renal, or hepatic disease diabetes mellitus

- Cancer in previous 5 years (except basal cell carcinoma of the skin)

- Any gastrointestinal disease or condition

- Recent bacterial infection (< 3 months)

- Recent or concurrent participation in an intervention research study

- History of drug or alcohol abuse in prior 6 months

- Use of lipid-lowering, anti-hypertensive, or anti-inflammatory steroid medication

- Eating disorder

- Vegetarians

- People who eat more than approximately 15 grams of fiber per day

- Women who are pregnant or lactating

- Women with irregular menstrual cycles



Age minimum: 18 Years
Age maximum: 64 Years
Gender: Both
Health Condition(s) or Problem(s) studied
Healthy
Intervention(s)
Dietary Supplement: Short chain fructo-oligosaccharide (scFOS) 5 g
Dietary Supplement: Short chain fructooligosaccharide (scFOS) 8 g
Other: Placebo
Primary Outcome(s)
Satiety response using visual analogue scales [Time Frame: 0, 15, 30, 45, 60, 90, 120, 180, 240 minutes postprandially]
Secondary Outcome(s)
Ad libitum food intake [Time Frame: 240 minutes postprandially and over 24 hours]
Breath hydrogen response [Time Frame: 0, 240 minutes]
Gastrointestinal tolerance using visual analogue scales (VAS) [Time Frame: 24 hours]
Secondary ID(s)
0806M37444
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
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