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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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27 May 2013 |
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Main ID: |
NCT01059240 |
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Date of registration:
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28/01/2010 |
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Primary sponsor: |
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Public title:
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SMN Copy Number Distribution in Mali, West Africa
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Scientific title:
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SMN Copy Number Distribution in Mali, West Africa |
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Date of first enrolment:
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January 2010 |
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Target sample size:
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1400 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT01059240 |
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Study type:
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Observational |
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Study design:
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Time Perspective: Prospective
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Countries of recruitment
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Mali
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Contacts
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Name:
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Modibo Sangare, M.D. |
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Address:
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Telephone:
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(301) 435-9319 |
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Email:
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sangarem@ninds.nih.gov |
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Affiliation:
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Name:
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Kenneth H Fischbeck, M.D. |
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Address:
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Telephone:
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Email:
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Affiliation:
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National Institute of Neurological Disorders and Stroke (NINDS) |
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Key inclusion & exclusion criteria
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- INCLUSION CRITERIA:
Medical students at the FMPOS of Malian ancestry and nationality who are 18 years of age
and above will be considered for this study.
EXCLUSION CRITERIA:
Subjects may not be eligible to participate if they have a condition that would make a
single 6 ml blood draw unsafe. Student assistants are ineligible for the study
participation.
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Spinal Muscular Atrophy
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Primary Outcome(s)
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Primary outcome measure for phase 1 is DNA extraction yield of sufficient quantity and quality for SMN genotyping in at least 90% of samples
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Secondary Outcome(s)
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Secondary outcome measures for phase 2 are the frequency of SMA carriers (SMN1 deletion heterozygotes) and the SMN1 and SMN2 copy number distribution in Mali.
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Secondary ID(s)
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10-N-N033
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999910033
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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