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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT01035307 |
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Date of registration:
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17/12/2009 |
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Primary sponsor: |
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Public title:
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Studying Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia Previously Enrolled on Clinical Trial POG-9421
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Scientific title:
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Genomic and Proteomic Profiling of Childhood AML |
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Date of first enrolment:
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October 2009 |
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Target sample size:
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90 |
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Recruitment status: |
Active, not recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT01035307 |
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Study type:
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Observational |
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Study design:
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N/A
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Contacts
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Name:
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Norman J. Lacayo, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Stanford University |
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Key inclusion & exclusion criteria
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DISEASE CHARACTERISTICS:
- Diagnosis of acute myeloid leukemia, meeting 1 of the following criteria:
- Primary induction failure (i.e., failed to achieve remission within the first 60
days of therapy)
- Relapsed disease (early or late)
- In continuous complete remission
- Previously enrolled on POG-9421
- Tissue samples available
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Age minimum:
N/A
Age maximum:
20 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Leukemia
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Intervention(s)
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Genetic: gene expression analysis
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Genetic: microarray analysis
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Genetic: proteomic profiling
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Other: laboratory biomarker analysis
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Primary Outcome(s)
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Classification of AML-based signal transduction mechanisms
[Time Frame: No]
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Correlation of basal and PPPN profiles with specific molecular lesions (e.g., FLT3-ITD, NPM, WT1, c-kit, CEPBa, PASG?75, and karyotype) and gene expression profiles.
[Time Frame: No]
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Profiling of basal and potentiated phospho-protein networks (PPPNs) using tissue samples
[Time Frame: No]
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Secondary ID(s)
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CDR0000659560
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COG-AAML09B2
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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