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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT01017796 |
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Date of registration:
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20/11/2009 |
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Primary sponsor: |
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Public title:
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Contrast Agent-associated Nephrotoxicity in Intensive Care Unit Patients
ICU |
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Scientific title:
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The Effect of Acetylcysteine and Ascorbic Acid on the Prevention of Radiographic-contrast-agent Induced Reduction in Renal Function in ICU Patients. |
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Date of first enrolment:
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January 2009 |
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Target sample size:
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100 |
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Recruitment status: |
Active, not recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT01017796 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Prevention
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Presence in the Intensive Care Unit
- Patients undergoing radiologic examinations with the use of IV contrast agents.
Exclusion Criteria:
- Renal failure under renal replacement therapy
- Unstable renal function ( change of serum creatinine between two subsequent days
greater than 20% at least 3 days before the study)
- IV administration of contrast agent within the previous 6 days from the study
- Use of ascorbic acid or acetylcysteine during the week before the study
- Pregnancy
Age minimum:
14 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Contrast Induced Nephropathy
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Intervention(s)
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Drug: N-acetylcysteine and ascorbic acid
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Primary Outcome(s)
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Morbidity in the Intensive Care Unit
[Time Frame: 1,5 year]
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Secondary Outcome(s)
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Incidence of acute nephropathy after administration of radiocontrast agents
[Time Frame: 1,5 year]
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Secondary ID(s)
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KIMNEF681264
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KN19201
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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