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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 17 October 2012
Main ID:  NCT00926198
Date of registration: 22/06/2009
Primary sponsor: Johann Wolfgang Goethe University Hospitals
Public title: Investigation of Clinical Spectrum, Bacterial Pathogens and Immune Response in Acute Pharyngotonsillitis
Scientific title: Frequency, Pathogen Spectrum and Specific Immune Response in Acute Pharyngotonsillitis in Children and Adolescents
Date of first enrolment: May 2009
Target sample size: 4500
Recruitment status: Completed
URL:  http://clinicaltrials.gov/show/NCT00926198
Study type:  Observational
Study design:  Observational Model: Cohort, Time Perspective: Cross-Sectional  
Countries of recruitment
Germany
Contacts
Name:   Stefan Zielen, Prof.
Address: 
Telephone:
Email:
Affiliation:  Medaimun GmbH and Johann Wolfgang Goethe University
Key inclusion & exclusion criteria

Inclusion Criteria:

- age 3 months to 18 years

- clinical signs of tonsillopharyngitis

- informed consent

Exclusion Criteria:

- age more than 18 years

- diagnosed chronic disease or infection (e.x. HIV, tuberculosis, malignancy)

- current participation in another research projects that may interfere with this study

- Incapability to perform all study procedure



Age minimum: 3 Months
Age maximum: 18 Years
Gender: Both
Health Condition(s) or Problem(s) studied
Tonsillitis
Intervention(s)
Primary Outcome(s)
The responsible pathogens (Frequency of GABHS) of acute pharyngotonsillitis and its clinical and serological response in children in a large urban setting. [Time Frame: 1 year]
Secondary Outcome(s)
In a subset of patients the immune response to GABHS will be measured at beginning and after 7 and 28 days. [Time Frame: one month]
Secondary ID(s)
KGU- 31/09
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
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