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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 7 January 2013
Main ID:  NCT00853073
Date of registration: 26/02/2009
Primary sponsor: Wills Eye
Public title: Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions? Avastin
Scientific title: Does a New Add on (or Adjunctive) Therapy Used in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?
Date of first enrolment: February 2009
Target sample size: 63
Recruitment status: Completed
URL:  http://clinicaltrials.gov/show/NCT00853073
Study type:  Interventional
Study design:  Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment  
Countries of recruitment
United States
Contacts
Name:   Marlene R Moster, MD
Address: 
Telephone:
Email:
Affiliation:  Wills Eye
Key inclusion & exclusion criteria

Inclusion Criteria:

- require glaucoma bleb needle revision with Mitomycin-C

Exclusion Criteria:

- pregnant, nursing, or not using adequate contraception

- other glaucoma eye surgery involving tube shunts

- prior retinal detachments surgery with scleral buckle

- infection, inflammation, or any abnormality preventing eye pressure measurement

- enrolled in another investigational study



Age minimum: 18 Years
Age maximum: N/A
Gender: Both
Health Condition(s) or Problem(s) studied
Glaucoma
Intervention(s)
Drug: bevacizumab
Other: balanced salt solution
Primary Outcome(s)
intraocular pressure (IOP) [Time Frame: 6 months]
Secondary Outcome(s)
improvement in filtering blebs morphology [Time Frame: 6 months]
Secondary ID(s)
08-867
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
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