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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT00721864 |
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Date of registration:
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23/07/2008 |
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Primary sponsor: |
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Public title:
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The Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH)
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Scientific title:
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The Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH) |
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Date of first enrolment:
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May 2006 |
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Target sample size:
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10 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00721864 |
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Study type:
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Observational |
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Study design:
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Observational Model: Cohort, Time Perspective: Prospective
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Countries of recruitment
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United States
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Contacts
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Name:
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Josef T Prchal, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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University of Utah |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
1. Subjects suspected of or diagnosed with Paroxysmal Nocturnal Hemoglobinuria (PNH)
2. Age > 7
Exclusion Criteria:
1. Those not meeting the inclusion criteria
Age minimum:
7 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Hemoglobinuria, Paroxysmal
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Primary Outcome(s)
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Identify the mutation causing the predominant clones through analysis of extracted DNA/RNA from erythroid colonies
[Time Frame: After sample is obtained]
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Secondary Outcome(s)
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Analysis of PrP function in human long term hematopoietic stem cells
[Time Frame: After sample is obtained]
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Reconfirmation of PrP expression in human granulocytes, hematopoietic progenitors and stem cells
[Time Frame: After sample is obtained]
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Secondary ID(s)
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17790
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R01HL5077-12
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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