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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT00713739 |
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Date of registration:
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07/07/2008 |
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Primary sponsor: |
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Public title:
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Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
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Scientific title:
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Evaluation of Alfuzosin as Medical Expulsion Therapy for Ureteral Stones |
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Date of first enrolment:
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January 2008 |
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Target sample size:
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240 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT00713739 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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Countries of recruitment
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United States
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Contacts
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Name:
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Brian K Auge, M.D. |
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Address:
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Telephone:
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619-532-7200 |
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Email:
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Affiliation:
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Name:
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Brian K. Auge, M.D. |
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Address:
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Telephone:
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619-532-7200 |
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Email:
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Affiliation:
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Name:
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Brian K. Auge, M.D. |
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Address:
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Telephone:
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Email:
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Affiliation:
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NMCSD |
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Name:
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Sean P. Stroup, M.D. |
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Address:
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Telephone:
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Email:
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Affiliation:
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NMCSD |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Age >/= 18 years
- Single ureteral stone < 1 cm in greatest dimension
Exclusion Criteria:
- Age < 18 years
- Active unstable angina
- History of or active postural hypotension (>20 mmHg drop in orthostatic SBP)
- Allergy to alpha-blockers
- Acute or Chronic Renal Failure as demonstrated by a serum creatinine of > 1.4 mg/dl
- Urinary tract infection
- Multiple ureteral stones
- Current uncontrolled diabetes
- Alpha-blocker therapy within 30 days for any reason
- Current pregnancy or lactation
- Patient desire for immediate stone removal
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Kidney Stones
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Intervention(s)
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Drug: Alfuzosin
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Drug: doxazosin
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Drug: nifedipine
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Drug: prazosin
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Primary Outcome(s)
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The primary measures are percent of stones passed and rates of occurrence of various side effects (categorical variables), and time to pass, pain scale, and amount of pain medication taken (continuous variables).
[Time Frame: Period of stone passage (30 days)]
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Secondary ID(s)
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NMCSD CID 06-050
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Office of Naval Research FY08
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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