Comparing the Efficacy of Different Zinc Formulations in the Treatment of Diarrhea

• Register: ClinicalTrials.gov
• Last refreshed on: 17 October 2012
• Main ID: NCT00682955
• Date of registration: 20/05/2008
• Primary sponsor: Aga Khan University
• Public title: Comparing the Efficacy of Different Zinc Formulations in the Treatment of Diarrhea Zinc
• Scientific title: Comparing the Efficacy of Different Zinc Formulations in the Treatment of Acute Diarrhea Among Young Children at Hospital Based Setting in Pakistan
• Date of first enrolment: August 2007
• Target sample size: 300
• Recruitment status: Completed
• URL: http://clinicaltrials.gov/show/NCT00682955
• Study type: Interventional
• Study design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Countries of recruitment

Pakistan

Key inclusion & exclusion criteria

Inclusion Criteria:

- Children 6 months to 5 years of age

- Presented with passage of 3 or more loose or watery stools

- Caretakers are willing to let their child to participate in the study.

Exclusion Criteria:

- Failure to produce consent.

- Children with severe malnutrition or having chronic illness



Age minimum: 6 Months
Age maximum: 5 Years
Gender: Both

Health Condition(s) or Problem(s) studied

Incidence of Abdominal Pain

Incidence of Acute Diarrhea

Intervention(s)

Drug: Zinc Sulphate

Primary Outcome(s)

Comparison of Efficacy of the two different Zinc Sulphate formulations [Time Frame: 9 months]

Secondary Outcome(s)

Comparison of side effects of the two different Zinc Sulphate formulations used [Time Frame: 9 months]

Secondary ID(s)

857-PED/ERC-07

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Civil Hospital, Hyderabad, Pakistan

National Institute of Child Health, Karachi, Pakistan