Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock

• Register: ClinicalTrials.gov
• Last refreshed on: 7 January 2013
• Main ID: NCT00604019
• Date of registration: 03/01/2008
• Primary sponsor: Rush University Medical Center
• Public title: Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock
• Scientific title: Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock
• Date of first enrolment: March 2003
• Target sample size: 251
• Recruitment status: Completed
• URL: http://clinicaltrials.gov/show/NCT00604019
• Study type: Interventional
• Study design: Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Countries of recruitment

United States

Contacts

• Name: Robert A Balk, MD
• Affiliation: Rush University Medical Center

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients are transferred to our medical intensive care unit from the emergency room
(ER), general medical floors, and from outside hospitals.

- Patients were eligible if they were greater than 18 years of age

- Presented with a diagnosis of SIRS plus a suspected or documented source of
infection.

Exclusion Criteria:

- Patients were not eligible if they were found to have hypovolemic and/or hemorrhagic
etiologies of their vasodilatory shock or another etiology of their SIRS.



Age minimum: 18 Years
Age maximum: N/A
Gender: Both

Health Condition(s) or Problem(s) studied

Septic Shock

Intervention(s)

Drug: Dopamine

Drug: Norepinephrine

Primary Outcome(s)

Efficacy [Time Frame: 28 days]

Secondary Outcome(s)

Safety, Arrythmia - Yes or no for Each Group [Time Frame: 28 days]

Secondary ID(s)

ORA-02102801

Source(s) of Monetary Support

Please refer to primary and secondary sponsors