Assessment of Cough Reflex in Lung Transplant Recipients

• Register: ClinicalTrials.gov
• Last refreshed on: 17 October 2012
• Main ID: NCT00584077
• Date of registration: 20/12/2007
• Primary sponsor: The University of Texas, Galveston
• Public title: Assessment of Cough Reflex in Lung Transplant Recipients
• Scientific title: Assessment of Cough Reflex in Lung Transplant Recipients
• Date of first enrolment: April 2000
• Target sample size: 36
• Recruitment status: Recruiting
• URL: http://clinicaltrials.gov/show/NCT00584077
• Study type: Observational
• Study design: Observational Model: Cohort, Time Perspective: Prospective

Countries of recruitment

United States

Contacts

• Name: Alexander G Duarte, MD

• Name: Alexander G Duarte, MD

• Name: Alexander G Duarte, MD
• Affiliation: University of Texas

Key inclusion & exclusion criteria

Inclusion Criteria:

- Lung transplant recipient

- Hemodynamically stable

- Capable of undergoing bronchoscopy

Exclusion Criteria:

- Pneumonia

- Hypoxemia (PaO2 < 70)

- Hemodynamic instability

- Coagulopathy

- Thrombocytopenia



Age minimum: 18 Years
Age maximum: N/A
Gender: Both

Health Condition(s) or Problem(s) studied

Lung Transplantion

Primary Outcome(s)

to evaluate presence and strength of the cough reflex in the lower airway specifically at the level of the main carina and airway anastomosis through the application of mechanical and chemical stimuli [Time Frame: 15-20 minutes]

Secondary Outcome(s)

to assess the presence and strength of the cough reflex in the lower airway for up to one year [Time Frame: 15-20 minutes]

Secondary ID(s)

00-132

Source(s) of Monetary Support

Please refer to primary and secondary sponsors