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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT00567242 |
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Date of registration:
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30/11/2007 |
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Primary sponsor: |
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Public title:
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Treating Intention In Aphasia: Neuroplastic Substrates
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Scientific title:
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Treating Intention In Aphasia: Neuroplastic Substrates |
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Date of first enrolment:
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March 2007 |
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Target sample size:
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14 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00567242 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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Countries of recruitment
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United States
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Contacts
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Name:
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Bruce Crosson, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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University of Florida |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Nonfluent aphasia caused by stroke
- Moderate to severe word-finding problems
- 6 or more months post stroke
- Right handed prior to stroke
- All strokes in left hemisphere
- Native English speaker
- Capable of following verbal directions
Exclusion Criteria:
- Severe impairment of word comprehension
- Brain injury or disease in addition to stroke
- Drug or alcohol abuse within past 6 months
- Schizophrenia or other psychiatric disorder necessitating hospitalization
- History of learning disability
- Claustrophobia
- Cardiac pace-maker
- Ferrous metal implants not attached to bone, metal fragments in body
- Profound hearing loss
Age minimum:
21 Years
Age maximum:
95 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Aphasia
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Cerebrovascular Accident
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Intervention(s)
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Behavioral: Word-finding with intention component
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Behavioral: Word-finding with no intention component
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Primary Outcome(s)
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Lateralization of Frontal Lobe (and Posterior Perisylvian) Activity During Word Production
[Time Frame: immediately post-treatment scan minus pre-treatment baseline scan]
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Secondary Outcome(s)
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Category Member Generation Probe Scores (% Accuracy)
[Time Frame: trend for time series of 8 baseline + 30 treatment sessions]
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Picture Naming Probe Scores (% Accuracy)
[Time Frame: trend for time series of 8 baseline + 30 treatment sessions]
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Secondary ID(s)
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R01DC007387
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R01DC007387-01A1
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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