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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT00540085 |
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Date of registration:
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04/10/2007 |
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Primary sponsor: |
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Public title:
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Pharmacodynamic Trial on Rocuronium in Obese Patients
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Scientific title:
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Pharmacodynamic Trial on Rocuronium in Obese Patients |
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Date of first enrolment:
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October 2007 |
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Target sample size:
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51 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00540085 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Prevention
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Countries of recruitment
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Denmark
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Contacts
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Name:
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Anne Marie Sørensen, MD, PhD |
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Address:
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Email:
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Affiliation:
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Department of anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Denmark |
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Name:
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Casper Claudius, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Denmark |
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Name:
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Christian S Meyhoff, MD, PhD |
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Address:
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Email:
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Affiliation:
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Department of anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Denmark |
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Name:
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Jørgen Viby-Mogensen, Prof., DMSc |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Denmark |
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Name:
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Lars S Rasmussen, MD, DMSc |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet, Denmark |
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Name:
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Jørgen Lund, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of anaesthesia, Privathospitalet Hamlet A/S, Denmark |
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Name:
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Morten Jenstrup, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of anaesthesia, Privathospitalet Hamlet A/S, Denmark |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Age 18-65 years.
- Elective laparoscopic gastric banding or gastric bypass.
Exclusion Criteria:
- Expected difficult endotracheal intubation based on anatomic or pathologic findings
or history.
- Known or suspected neuromuscular disease, known to affect the neuromuscular blockade.
- Severely impaired renal or hepatic function, as evaluated by the investigator.
- Known or suspected allergy to drugs used in the trial.
- Daily or expected use during the trial of the following drugs, known to affect
neuromuscular transmission: Inhalational anaesthetics, magnesiumsalts, clindamycin,
polymyxins and aminoglycosides (gentamicin, neomycin, netilmicin, streptomycin og
tobramycin).
Age minimum:
18 Years
Age maximum:
65 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Bariatric Surgery
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Intervention(s)
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Drug: Rocuronium
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Primary Outcome(s)
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Duration of action, defined as: Time to reappearance of T4.
[Time Frame: 1 day]
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Secondary Outcome(s)
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Complete duration of action, defined as: Time to TOF-ratio = 0.9
[Time Frame: 1 day]
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Onset time
[Time Frame: 1 day]
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Secondary ID(s)
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2007-003005-27
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H-B-2007-038
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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