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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 17 October 2012
Main ID:  NCT00445835
Date of registration: 08/03/2007
Primary sponsor: Assistance Publique - Hôpitaux de Paris
Public title: Active Detection of the Extension of Atherothrombosis in High Risk Coronary Patients AMERICA
Scientific title: Active Detection and Management of the Extension of Atherothrombosis in High Risk Coronary Patients In Comparison With Standard of Care for Coronary Atherosclerosis: The AMERICA Study
Date of first enrolment: September 2007
Target sample size: 526
Recruitment status: Active, not recruiting
URL:  http://clinicaltrials.gov/show/NCT00445835
Study type:  Interventional
Study design:  Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment  
Countries of recruitment
France
Contacts
Name:   Jean-Philippe COLLET, MD PhD
Address: 
Telephone:
Email:
Affiliation:  Assistance Publique - Hôpitaux de Paris
Key inclusion & exclusion criteria

Inclusion criteria:

1. Three vessel disease recently identified recently (<6 month)

2. Accrue coronary syndromes in patients>75 years old (<1 month)

Exclusion criteria:

1. Absence of significant coronary lesions

2. Other causes of rise in the troponin level

3. Patient<18 years old

4. Pregnant women

5. Patient without affiliation to National Social Security



Age minimum: 18 Years
Age maximum: N/A
Gender: Both
Health Condition(s) or Problem(s) studied
Coronary Artery Disease
Intervention(s)
Other: Arterial doppler for screening asymptomatic and significant extracoronary arterial stenoses in all arterial beds
Other: Conservative arm
Primary Outcome(s)
death (all cause) or any ischemic event leading to rehospitalisation or any evidence of organ failure. [Time Frame: during the study]
Secondary Outcome(s)
Incidence of each composite of the primary endpoint. [Time Frame: during the study]
Secondary ID(s)
P060902
PHAO 2006
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Institut de l'Atherothrombose
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