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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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7 January 2013 |
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Main ID: |
NCT00224185 |
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Date of registration:
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20/09/2005 |
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Primary sponsor: |
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Public title:
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Evaluation of Lungs of Normal Individuals by Lung Lavage, Brushing and Bronchial Wall Biopsy
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Scientific title:
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Evaluation of the Lungs of Normal Individuals With Segmental Bronchopulmonary Lung Lavage, Bronchial Brushing and Bronchial Wall Biopsy |
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Date of first enrolment:
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January 2004 |
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Target sample size:
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196 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00224185 |
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Study type:
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Observational |
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Study design:
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Observational Model: Case-Only, Time Perspective: Prospective
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Countries of recruitment
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United States
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Contacts
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Name:
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Ronald G Crystal, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Department of Genetic Medicine, Weill Cornell Medical College |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- All study subjects should be able to provide informed consent
- Males or females ages 18 years and older.
- Must provide HIV informed consent.
- Non-smokers, ex-smokers and smokers.
Exclusion Criteria:
- Individuals not deemed in good overall health by the investigator will not be
accepted into the study.
- Drug and/or alcohol abuse within the past six months.
- Individuals with history of chronic lung disease, including asthma or with recurrent
or recent (within three months) acute pulmonary disease will not be accepted into the
study.
- Individuals with allergies to atropine or any local anesthetic will not be accepted
into the study.
- Individuals with allergies to pilocarpine, isoproterenol, terbutaline, atropine or
aminophylline will not be accepted into the study
- Females who are pregnant or nursing will not be accepted into the study
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Lung Diseases
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Smoking
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Intervention(s)
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Procedure: Bronchial Brushing
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Procedure: Bronchial Wall Biopsy
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Procedure: Bronchopulmonary Lung Lavage
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Primary Outcome(s)
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Evaluate etiology of lung diseases
[Time Frame: 9/31/2012]
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Secondary Outcome(s)
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Effect of smoking on the genes of airway epithelial cells
[Time Frame: 9/31/2012]
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Secondary ID(s)
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IRB0005004439
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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