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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 17 October 2012
Main ID:  NCT00181090
Date of registration: 10/09/2005
Primary sponsor: Johns Hopkins University
Public title: Use of the Atkins Diet for Children With Intractable Epilepsy: A Comparison of Daily Carbohydrate Limits
Scientific title:
Date of first enrolment: February 2005
Target sample size: 30
Recruitment status: Completed
URL:  http://clinicaltrials.gov/show/NCT00181090
Study type:  Interventional
Study design:  Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment  
Countries of recruitment
United States
Contacts
Name:   Eric H Kossoff, MD
Address: 
Telephone:
Email:
Affiliation:  Johns Hopkins University
Key inclusion & exclusion criteria

Inclusion Criteria:

- Ages 3-18

- Daily seizures or 7 per week

- Failed at least 2 anticonvulsants

Exclusion Criteria:

- Prior use of the Atkins diet for over 1 week

- Significant heart, liver, or kidney disease



Age minimum: 3 Years
Age maximum: 18 Years
Gender: Both
Health Condition(s) or Problem(s) studied
Epilepsy
Intervention(s)
Behavioral: Modified Atkins diet
Primary Outcome(s)
Ketosis [Time Frame: 6 months]
Seizure control [Time Frame: 6 months]
Secondary Outcome(s)
Safety - cholesterol, kidney function, weight [Time Frame: 6 months]
Tolerability [Time Frame: 6 months]
Secondary ID(s)
05-01-26-05
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
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