|
Main
|
|
Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
|
Register:
|
ClinicalTrials.gov |
|
Last refreshed on:
|
17 October 2012 |
|
Main ID: |
NCT00169364 |
|
Date of registration:
|
12/09/2005 |
|
Primary sponsor: |
|
|
Public title:
|
Clinical, Molecular and Metabolic Characteristics of Parkinson's Disease (PD) Patients With Parkin Mutation
|
|
Scientific title:
|
Comparison of Clinical, Molecular and Metabolic Characteristics of PD Patients With and Without Parkin Mutation |
|
Date of first enrolment:
|
May 2002 |
|
Target sample size:
|
50 |
|
Recruitment status: |
Recruiting |
|
URL:
|
http://clinicaltrials.gov/show/NCT00169364 |
|
Study type:
|
Interventional |
|
Study design:
|
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
|
|
|
Countries of recruitment
|
|
France
| | | | | | | |
|
Contacts
|
|
Name:
|
Marie-Laure Welter, MD |
|
Address:
|
|
|
Telephone:
|
33-142161950 |
|
Email:
|
marie-laure.welter@psl.aphp.fr |
|
Affiliation:
|
|
|
|
Name:
|
Alexis Brice, MD, PhD |
|
Address:
|
|
|
Telephone:
|
33-142162183 |
|
Email:
|
brice@ccr.jussieu.fr |
|
Affiliation:
|
|
|
|
Name:
|
Alexis Brice, MD, PhD |
|
Address:
|
|
|
Telephone:
|
|
|
Email:
|
|
|
Affiliation:
|
Groupe Hospitalier Pitié-Salpêtrière |
|
|
Key inclusion & exclusion criteria
|
Inclusion Criteria:
- Juvenile Parkinson's disease (< 45 years)
- Parkin mutation
- Normal brain magnetic resonance imaging (MRI)
Exclusion Criteria:
- Contraindication to brain MRI
- Women without effective contraception
Age minimum:
18 Years
Age maximum:
80 Years
Gender:
Both
|
|
Health Condition(s) or Problem(s) studied
|
|
Parkinson's Disease
|
|
Intervention(s)
|
|
Device: positron emission tomography
|
|
Primary Outcome(s)
|
|
Motor disability
|
|
Neuropsychological evaluation
|
|
Parkin mutation
|
|
Psychiatric evaluation
|
|
Secondary Outcome(s)
|
|
Positron emission tomography
|
|
Source(s) of Monetary Support
|
|
Please refer to primary and secondary sponsors
|
|