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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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17 October 2012 |
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Main ID: |
NCT00072813 |
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Date of registration:
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10/11/2003 |
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Primary sponsor: |
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Public title:
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MRI in Autosomal Dominant Partial Epilepsy With Auditory Features
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Scientific title:
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MRI in Autosomal Dominant Partial Epilepsy With Auditory Features |
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Date of first enrolment:
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November 2003 |
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Target sample size:
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72 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00072813 |
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Study type:
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Observational |
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Study design:
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N/A
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Countries of recruitment
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United States
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Key inclusion & exclusion criteria
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- INCLUSION CRITERIA:
Patients and family members in kindreds with ADPEAF evaluated by Dr. Ruth Ottman at CPMC:
14 patients with seizures and the LGl1 mutation.
14 family members with the mutation but no seizures.
14 Non-affected family members, who are not carriers of the LGl1 mutation.
30 normal controls selected at NIH, and screened in the CES outpatient clinic with a
physical and neurological examination.
EXCLUSION CRITERIA:
Subjects unable or unwilling to undergo MRI, EEG, and MEG.
Women who are pregnant.
Subjects under 18.
Subjects with medical conditions other than ADPEAF that may affect brain function.
Subjects taking medications or neuroactive substances that may affect brain function.
Healthy volunteers must be below the age of 55, to reduce the chance of vascular chnages
that could affect MRI.
Age minimum:
21 Years
Age maximum:
65 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Epilepsies, Partial
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Secondary ID(s)
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04-N-0033
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040033
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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