Search genes as risk factors related with development and phenotype of COPD.

• Register: KCT
• Last refreshed on: 27 April 2013
• Main ID: KCT0000371
• Date of registration: 29/02/2012
• Primary sponsor: THE MINISTRY OF HEALTH AND WELFARE
• Public title: Search genes as risk factors related with development and phenotype of COPD.
• Scientific title: Study on genes as risk factors related with development and phenotype of COPD.
• Date of first enrolment: 2012-02-29
• Target sample size: 2000
• Recruitment status: Not yet recruiting
• URL: http://cris.nih.go.kr/cris/en/search/search_result_st01.jsp?seq=1898
• Study type: Observational Study
• Study design: Observational Study Model : Case-control, Time Perspective : Cross-sectional, Enrollment : 2000, Biospecimen Retention : Retained - Sample with DNA, Biospecimen Description : DNA

Countries of recruitment

Korea, Republic of

Contacts

• Name: SANGDO LEE
• Affiliation: ASAN MEDICAL CENTER

• Name: YEON-MOK OH
• Affiliation: ASAN MEDICAL CENTER

Key inclusion & exclusion criteria

Inclusion criteria: *Patients with COPD
1. Out-patient Men or Women >40 years of age
2. Current or previous smoker with a history of smoking equivalent to 20 or more pack years.
3. FEV1/FVC<0.7, Post-bronchodilator
*Control group
1. Health Examination Center Men or Women >40 years of age
2. Current or previous smoker with a history of smoking equivalent to 20 or more pack years.
3.Normal Pulmonary Function Test
Exclusion criteria: 1.Physician-diagnosed asthma
2. Tuberculous destroyed lung
3. Bronchiectasia
4. Pneumonectomy
5. Other diseases like cancers, heart failure.

Age minimum: 40(Year)
Age maximum: 99(Year)
Gender: Both

Health Condition(s) or Problem(s) studied

Diseases of th respiratory system

Primary Outcome(s)

Odds ratio of genic pleomorphic frequency

Secondary Outcome(s)

Genic Plemorphic frequency

Secondary Sponsor(s)

ASAN MEDICAL CENTER-CLINICAL RESEARCH CENTER FOR CHRONIC OBSTRUCTIVE AIRWAY DISEASES