Variability in Systolic Blood Pressure as a predictor Poor Cognitive Function

• Register: KCT
• Last refreshed on: 27 April 2013
• Main ID: KCT0000293
• Date of registration: 16/12/2011
• Primary sponsor: Sanofi aventis Korea Lt.
• Public title: Variability in Systolic Blood Pressure as a predictor Poor Cognitive Function
• Scientific title: Multicenter Retrospective Study of Variability in Systolic Blood Pressure as a Predictor of Poor Cognitive Function
• Date of first enrolment: 2012-02-01
• Target sample size: 189
• Recruitment status: Not yet recruiting
• URL: http://cris.nih.go.kr/cris/en/search/search_result_st01.jsp?seq=1691
• Study type: Observational Study
• Study design: Observational Study Model : Cohort, Time Perspective : Prospective, Enrollment : 189, Biospecimen Retention : None Retained

Countries of recruitment

Korea, Republic of

Contacts

• Name: Byung-Chul Lee
• Affiliation: Hallym University Sacred Heart Hospital

• Name: Ju Hun Lee
• Affiliation: Kangdong Sacred Heart Hospital

Key inclusion & exclusion criteria

Inclusion criteria: a. age 45~80 years
b. patients with smalll vessel disease assessed by on brain MRI at 24~48 months ago
Exclusion criteria: a. No informed consent
b. patient has not measured six or more blood pressure during 24 months
c. patient has a hisotry stroke or coronary artery disease in the past 24 months
d. patient has symptomatic significant cerebral artery stenosis
e. patient has atrial fibrillation on EKG or high risk of cardioembolic source
f. patient had been treated acetylcholine essterase inhibitor or memantine

Age minimum: 45(Year)
Age maximum: 80(Year)
Gender: Both

Health Condition(s) or Problem(s) studied

Diseases of the nervous system

Primary Outcome(s)

mean K-MMSE

Secondary Outcome(s)

K-VCIHS NP 30-minute protocol

Secondary Sponsor(s)

Hallym University Sacred Heart Hospital