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Main
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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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JPRN |
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Last refreshed on:
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27 May 2013 |
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Main ID: |
JPRN-UMIN000002931 |
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Date of registration:
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23/12/2009 |
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Primary sponsor: |
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Public title:
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The influence of polymorphism in methotrexate pathway genes on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis
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Scientific title:
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Date of first enrolment:
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2007/05/01 |
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Target sample size:
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100 |
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Recruitment status: |
Completed |
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URL:
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http://www.umin.ac.jp/ctr/index.htm |
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Study type:
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Observational |
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Study design:
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Countries of recruitment
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Japan
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Contacts
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Name:
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Address:
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Japan |
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Telephone:
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m-yanagi@mvi.biglobe.ne.jp |
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Email:
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m-yanagi@mvi.biglobe.ne.jp |
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Affiliation:
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Name:
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Address:
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Japan |
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Telephone:
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045-787-2800 |
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Email:
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Affiliation:
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Yokohama City University School of Medicine Pediatrics |
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Key inclusion & exclusion criteria
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Inclusion criteria: The patients with juvenile idiopathic arthritis who were treated with MTX in our hospital and with prior written informed consent from patients and/or their parents.
Exclusion criteria: The patient who was judged by physicians as an improper case for enrollment in this study
Age minimum:
Not applicable
Age maximum:
18years-old
Gender:
Male and Female
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Health Condition(s) or Problem(s) studied
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Articular-type juvenile idiopathic arthritis (JIA)
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Primary Outcome(s)
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Efficacy and toxicity of methotrexate in patients with JIA
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Secondary Outcome(s)
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Subgroup analysis based on (1)time interval between onset and treatment, (2)response to therapy, (3)the level of anti-citrullinated peptide antibodies, and rheumatoid factor.
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Source(s) of Monetary Support
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Health and labour Sciences Research Grants
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