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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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JPRN |
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Last refreshed on:
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17 October 2023 |
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Main ID: |
JPRN-UMIN000001462 |
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Date of registration:
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29/10/2008 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Effective of hANP for cardiac surgery in patients with moderate to severe preoperative renal dysfunction without dialysis.
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Scientific title:
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Effective of hANP for cardiac surgery in patients with moderate to severe preoperative renal dysfunction without dialysis. - NU-HIT trial for CRF |
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Date of first enrolment:
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1997/03/01 |
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Target sample size:
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100 |
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Recruitment status: |
Complete: follow-up complete |
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URL:
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https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000001778 |
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Study type:
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Interventional |
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Study design:
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Parallel Randomized
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Phase:
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Phase II
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Countries of recruitment
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Japan
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Contacts
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Name:
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Akira Sezai |
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Address:
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30-1 Oyaguchi kami-machi, Itabashi-ku, Tokyo, Japan
Japan |
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Telephone:
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03-3972-8111 |
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Email:
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Affiliation:
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Nihon University School of Medicine Department of Cardiovascular Surgery |
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Name:
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Akira Sezai |
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Address:
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30-1 Oyaguchi kami-machi, Itabashi-ku, Tokyo, Japan
Japan |
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Telephone:
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03-3972-8111 |
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Email:
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asezai.med@gmail.com |
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Affiliation:
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Nihon University School of Medicine Department of Cardiovascular Surgery |
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Key inclusion & exclusion criteria
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Inclusion criteria:
Exclusion criteria: cardiogenic shock dialysis-dependent patient
Age minimum:
20years-old
Age maximum:
80years-old
Gender:
Male and Female
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Health Condition(s) or Problem(s) studied
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myocardial infarction, angina, valvular disease, thoracic aortic aneurysm
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Intervention(s)
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Perioperative administration of hANP
Perioperative non-administration of hANP
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Primary Outcome(s)
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presence of dialysis eGFR
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Secondary Outcome(s)
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mortality ,survival rate ,complication, BNP, ANP, renin activity, angiotensin II, aldosterone, blood urea reno-event free rate, nitrogen (BUN), Cr, sodium (Na), osmotic pressure (Osm),Urinary Na (U-Na), urinary Cr (U-Cr), and osmotic pressure (U-osm) creatinine clearance Ccr, fractional sodium excretion, free water clearance and renal failure index
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Source(s) of Monetary Support
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self funding
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a grant for the 60th anniversary of the Alumni Association of Nihon University School of Medicine and for the 50th anniversary of the foundation of Nihon University School of Medicine.
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Ethics review
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Status: YES
Approval date:
Contact:
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Results
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Results available:
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Yes |
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Date Posted:
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Date Completed:
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01/05/2009 |
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URL:
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