UKALL R2 - Acute Lymphoblastic Leukaemia trial

• Register: ISRCTN
• Last refreshed on: 12 February 2013
• Main ID: ISRCTN95257778
• Date of registration: 06/04/2000
• Primary sponsor: Medical Research Council (MRC) (UK)
• Public title: UKALL R2 - Acute Lymphoblastic Leukaemia trial UKALL R2
• Date of first enrolment: Feb 1 1995
• Target sample size: 200 - Closed to recruitment - in long term follow-up
• Recruitment status: Completed/Not recruiting
• URL: http://isrctn.org/ISRCTN95257778
• Study type: Interventional
• Study design: Randomised controlled trial

Countries of recruitment

United Kingdom

Contacts

• Name: PJ Darbyshire

Key inclusion & exclusion criteria

Inclusion criteria: They are children under 15 years at original diagnosis and treated on UKALL trials or pilot studies with first relapse less than 4 years from the start of treatment of ALL at any site and no suitable related bone marrow treatment (BMT) donor is available
Exclusion criteria: 1. They are multiply relapsed patients
2. They have a prior history of toxicity or organ damage such that completion of the protocol is felt unlikely at the outset
3. They have had an isolated CNS or testicular relapse more than 6 months off treatment.

Age minimum:
Age maximum:
Gender:

Health Condition(s) or Problem(s) studied

Acute Lymphoblastic Leukaemia

Intervention(s)

Continuing chemotherapy/unrelated donor BMT

Primary Outcome(s)

Survival, disease free survival

Secondary Outcome(s)

Not provided at time of registration

Secondary ID(s)

G8223452

Source(s) of Monetary Support

UK Medical Research Council

Secondary Sponsor(s)

N/A