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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ISRCTN
Last refreshed on: 12 February 2013
Main ID:  ISRCTN81324728
Date of registration: 30/09/2005
Primary sponsor: Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Public title: A comparison of the effects of Sevoflurane and Isoflurane on cardiovascular parameters measured by cardiac magnetic resonance imaging in paediatric patients with congenital heart disease. A randomised controlled trial. N/A
Scientific title:
Date of first enrolment: Sep 1 2003
Target sample size: 10
Recruitment status: Completed/Not recruiting
URL:  http://isrctn.org/ISRCTN81324728
Study type:  Interventional
Study design:  Randomised controlled trial  
Countries of recruitment
United Kingdom
Contacts
Name: Priti  Dalal
Address:  Theatres 2nd Floor, New Guy House Guy's Hospital St Thomas' Street SE1 9RT London United Kingdom
Telephone:
Email:
Affiliation: 
Key inclusion & exclusion criteria
Inclusion criteria: Subjects will be children with congenital cardiac abnormalities who are undergoing magnetic resonance imaging to achieve an accurate diagnosis and determine future treatment options.
Exclusion criteria: 1. Patient or parental refusal
2. Allergic, anaphylactic or other reactions to inhalational anaesthetic agents
3. Patients older than 16 years of age.


Age minimum:
Age maximum:
Gender:
Health Condition(s) or Problem(s) studied
Heart disease
Intervention(s)
The routine study usually lasts 1 hour. For the first 30 minutes, each subject will be anaesthetised with one of the agents. The agent will then be swapped and the patients anaesthetised with the other agent for the remaining 30 minutes. Variables will be recorded at the end of each period.
Primary Outcome(s)
Cardiac output, aortic and pulmonary blood flow, arterial pressure, systemic vascular resistance.
Secondary Outcome(s)
Not provided at time of registration
Secondary ID(s)
N0013145919
Source(s) of Monetary Support
Guy's and St. Thomas' NHS Foundation Trust (UK) Own account, NHS R&D Support Funding
Secondary Sponsor(s)
N/A
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